منابع مشابه
Pharmacological control of gastric acid secretion: molecular and cellular aspects.
Chronic ulceration of the gastroduodenal mucosa is one of the most common, so called "civilization diseases" of the gastrointestinal tract in industrially developed countries. Although the primary cause of gastric and duodenal peptic ulcers is unknown, gastric acid secretion is believed to play an important role in this major pathology. Gastric peptic ulcers, which represent 20% of all peptic u...
متن کاملGastric acid secretion.
PURPOSE OF REVIEW The present review summarizes the past year's literature, both clinical and basic science, regarding neuroendocrine and intracellular regulation of gastric acid secretion and proper use of antisecretory medications. RECENT FINDINGS Gastric acid kills microorganisms, modulates the gut microbiome, assists in digestion of protein, and facilitates absorption of iron, calcium, an...
متن کاملEffect of Esophageal Distention on Basal and Stimulated Gastric Acid Secretion in Rats
It is well established that the esophageal distention (ED) leads to gastric relaxation, partly by vago-vagal reflex, but till now, the effect of ED on gastric acid secretion has not been investigated. The aim of this study was to investigate the effect of ED on basal and stimulated gastric acid secretion. Methods: Adult male Wistar rats (200-240 g) were deprived of food but not the water 24 h b...
متن کاملEffects of endogenous production and exogenous administration of H2S on gastric acid secretion in rats
Introduction: Recently, hydrogen sulfide has been introduced as the third gas that acts as a transmitter. It has many physiological and pharmacological roles in the human body. The aim of the present study was to investigate the effect of exogenously administered and endogenously produced H2S on the basal and distention-induced gastric acid secretion in rats. Methods: Forty-nine male Wistar...
متن کاملEffect of Nimbidin on Gastric Acid Secretion
Nimbidin, the crude bitter compound from neem has been investigated for its gastric anti secretory activity in rats and cats. It exhibited significant anti - secretory activity in pylorus ligated rats and cats. In lumen - perfused rats it suppressed the basal as well as histamine and carbachol stimulated gastric acid output at 40 mg/kg (i.v). However it had no effect on ASA - induced back - dif...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1979
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.76.12.6689